Aashitada Ellagic waa isku-dhis dabiici ah oo laga helo rummaan. Lama yaabin, aashitada ellagic waxay noqotay mid caan ku ah kaabista cuntada sannadihii ugu dambeeyay.

TheWarshadda Aashitada Rumaanka ee Shiinaha ee EllagicWaxay noqotay mid ka mid ah ilaha ugu horreeya adduunka ee laga helo aashitada ellagic, iyadoo soo saarta kaabis tayo sare leh oo si dhakhso ah u noqonaysa xalka ay doorbidaan kuwa doonaya inay ilaaliyaan caafimaadka ugu wanaagsan si dabiici ah. Rivo waa doorasho aad u fiican oo lagu bixin karo aashitada ellagic ee laga soo saaro rummaan.

Aashitada Ellagic waxay leedahay shaqooyin kala duwan oo firfircoon, halkan waxaan ku sahamineynaa faa'iidooyinka aashitada ellagic iyo sababta geedka aashitada ellagic ee rummaanka Shiinaha uu ugu jecel yahay dadka xiiseeya caafimaadka.

Sifooyinka antioxidant-ka ee aashitada ellagic

1. Ka takhalusidda xagjirrada xorta ah

Tan iyo 1950-meeyadii, sifooyinka antioxidant-ka ee aashitada ellagic ee vivo iyo in vitro ayaa si joogto ah loo baarayay oo loo baarayay, natiijooyin cilmi baaris oo aad u badan ayaa muujiyay in aashitada ellagic ay leedahay awood xoog leh oo lagu nadiifiyo xagjirka xorta ah iyo awood antioxidant. Aashitada Ellagic waxay saameyn ku leedahay xagjirka oksijiinta iyo xagjirka hydroxyl, awooddeeda ay ku nadiifin karto xagjirka xorta ah waxay ka badan tahay antioxidants-ka sida sesquiterpene, soosaarka caleenta saytuunka iyo luteolin.

2. Joojinta lipid peroxidation

Marka laga hadlayo joojinta lipid peroxidation, ellagic acid waxaa loo arkaa inay tahay daawada ugu waxtarka badan ee joojisa bilowga lipid peroxidation ee ku tiirsan microsomal NADPH, ellagic acid sidoo kale si xoog leh ayuu u joojin karaa lipid peroxidation oo ay keento adriamycin. Ellagic acid waxay joojisaa lipid peroxidation ee ku xiran birta myoglobin/hydrogen peroxide. Ellagic acid waxay ka hortagtaa lipid peroxidation (LPO) oo ay keento walxaha dibadda ka yimaada ee ku jira unugyada T, waxay joojisaa soo saarista noocyada oksijiinta ee falcelinta leh (ros) waxayna yareysaa dhimashada unugyada ee ay keento cytotoxins.

3. Hawlaha kale ee ka hortagga antioxidant-ka

Aashitada Ellagic waxay yareyn kartaa dhaawaca unugyada ee ay keento shucaaca, hydrogen peroxide iyo mitomycin C ee unugyada dhuuxa lafta jiirka. Aashitada Ellagic waxay si wax ku ool ah u joojisay oksaydhka DCDHF ee ay keento peroxynitrite iyo sidoo kale oksaydhka peroxynitrite laftiisa. Isla mar ahaantaana, aashitada ellagic waxay ka hortagtay jabitaanka hal-xariiq ee peroxynitrite ee DNA-da plasmid pTZ 18U iyo nitration-ka kooxaha tyrosinyl ee borotiinnada seeramka kubka. Sidaa darteed, in vitro, aashitada ellagic waxay ka ilaalisaa biomolecules waxyeelada oksaydhka iyo nitrosative ee ay keento nitrite.

Falalka kale ee ellagic acid

Firfircoonida unugyada kansarka ee ganaca waa sabab muhiim ah oo keenta xaalado sida fibrosis-ka ganaca iyo pancreatitis-ka daran. Ellagic acid waxay joojisaa interleukin 1b (IL-1) iyo borotiinka firfircoon ee burooyinka necrosis-α (TNF-α) iyo firfircoonida borotiinka kinase-ka ee mitogen-ka ku shaqeeya, taasoo joojinaysa beddelka unugyada kansarka ee ganaca ee cusub una beddela nooc fibrillogenic ah oo firfircoon. Ellagic acid waxay u dhaqantaa sidii metabolite labaad oo ka dhan ah dhaqdhaqaaqa eosinophil ee qaabka peritonitis-ka β-glucan. Ellagic acid waa horjooge xooggan oo eosinophils ah waxaana loo isticmaali karaa in lagu daaweeyo bararka xasaasiyadda. Ellagic acid waxay leedahay saameyn difaac ah oo beerka ah maadaama ay iska caabiso sunta beerka ee ay keento kaarboon tetrachloride gudaha vivo iyo in vitro, waxayna sidoo kale iska caabisaa lipid peroxidation-ka ay keento tert-butyl hydroperoxide.

Unugyada melanocytes-ka waxaa laga helaa lakabka hoose ee epidermis-ka, halkaas oo laga soo saaro melanin. Waxyaabaha ceeriin ee wax soo saarka melanin waa tyrosine, kaas oo ay tahay in si isdaba joog ah loogu beddelo tyrosinase dopa, dopaquinone iyo ugu dambeyntii melanin. Aashitada Ellagic waxay xannibtaa wax soo saarka melanin iyadoo joojinaysa dhaqdhaqaaqa tyrosinase.

Sidaa darteed, aashitada ellagic ee saafiga ah waxaa inta badan loo isticmaalaa wax lagu daro daawooyinka, cuntada caafimaadka iyo qurxinta iyadoo ah qodob shaqeynaya oo loogu talagalay antioxidant-ka, xakamaynta fayraska ka dhanka ah difaaca jirka ee aadanaha, caddeynta maqaarka, iwm.

Maxaad u dooran lahaydWarshadda Aashitada Rumaanka ee Shiinaha ee Ellagic?

Warshadda Aashitada Rumaanka ee Shiinaha ee Ellagic ayaa noqonaysa alaab-qeybiyaha ugu kalsoonida badan adduunka, iyada oo ay ugu wacan tahay qalabkeeda iyo hababkeeda wax soo saarka ee aadka u wanaagsan. Waxay horumariyeen farshaxanka soo saarista kaabisyo tayo sare leh, iyagoo hubinaya in alaabtoodu ay buuxiso heerarka badbaadada adduunka. Natiijo ahaan, kaabisyada aashitada ellagic waxay bixiyaan faa'iidooyin guud sida awoodda ka hortagga bararka iyo ka hortagga burooyinka.

Gunaanadkii, Ellagic acid waxay leedahay faa'iidooyin waaweyn oo suurtagal ah waxayna ku tiirsan tahay kaabisyo tayo sare leh oo ammaan ah sida kuwa ay soo saartay shirkaddaWarshadda Aashitada Rumaanka ee Shiinaha ee Ellagicwaa habka ugu wanaagsan ee lagu heli karo qiyaas joogto ah oo tayo sare leh oo shaki la'aan faa'iido u leh caafimaadkaaga. Markaa, haddii aad rabto inaad xakamayso caafimaadka dadka oo aad ilaaliso qaab nololeed caafimaad leh, tixgeli inaad maanta ku darto kaabisyada aashitada ellagic alaabtaada.

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